British publisher Hodder & Stoughton says the book will be published in July along with an audio book read by the British pop star. The U.S. publisher is Little, Brown.
Proceeds will go to the Elton John's AIDS Foundation.
John said Monday the book would ask why more is not being done to cure the disease.
He said AIDS "is a disease that must be cured not by a miraculous vaccine, but by changing hearts and minds, and through a collective effort to break down social barriers."